E22K (p.Glu22Lys) variant of IL1RN (P18510)
E22K (p.Glu22Lys) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
E22K (p.Glu22Lys) variant details
- p.Glu22Lys
- gnomAD 2-113120107-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- MetaLR 0.05
- MetaSVM -1.02
- CADD 8.91
- SIFT 0.63
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available