E22D (p.Glu22Asp) variant of IL1RN (P18510)
E22D (p.Glu22Asp) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
E22D (p.Glu22Asp) variant details
- p.Glu22Asp
- gnomAD 2-113120103-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- MetaLR 0.04
- MetaSVM -1.05
- CADD 0.01
- SIFT 0.83
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available