D42G (p.Asp42Gly) variant of IL1RN (P18510)
D42G (p.Asp42Gly) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
D42G (p.Asp42Gly) variant details
- p.Asp42Gly
- rs144607130
- gnomAD 2-113120111-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- MetaLR 0.06
- MetaSVM -0.98
- CADD 1.87
- SIFT 0.52
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available