C4R (p.Cys4Arg) variant of IL1RN (P18510)
C4R (p.Cys4Arg) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
C4R (p.Cys4Arg) variant details
- p.Cys4Arg
- gnomAD 2-113127634-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0557
- REVEL 0.02
- CADD 7.14
- PolyPhen-2 0.00
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available