A57T (p.Ala57Thr) variant of IL1RN (P18510)
A57T (p.Ala57Thr) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
A57T (p.Ala57Thr) variant details
- p.Ala57Thr
- gnomAD 2-113129628-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.29
- MetaLR 0.10
- MetaSVM -0.97
- CADD 25.00
- PolyPhen-2 0.81
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available