Y59H (p.Tyr59His) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
Y59H (p.Tyr59His) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
Y59H (p.Tyr59His) variant details
- p.Tyr59His
- gnomAD X-105195567-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.574
- REVEL 0.59
- MetaLR 0.60
- MetaSVM 0.17
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available