S27Y (p.Ser27Tyr) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
S27Y (p.Ser27Tyr) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
S27Y (p.Ser27Tyr) variant details
- p.Ser27Tyr
- gnomAD X-104658993-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.20
- MetaLR 0.04
- MetaSVM -1.21
- CADD 26.80
- PolyPhen-2 0.96
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available