S27T (p.Ser27Thr) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
S27T (p.Ser27Thr) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
S27T (p.Ser27Thr) variant details
- p.Ser27Thr
- gnomAD X-104658992-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.15
- MetaLR 0.02
- MetaSVM -0.96
- CADD 22.90
- PolyPhen-2 0.83
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available