S23A (p.Ser23Ala) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
S23A (p.Ser23Ala) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
S23A (p.Ser23Ala) variant details
- p.Ser23Ala
- gnomAD X-104658980-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.13
- MetaLR 0.02
- MetaSVM -0.95
- CADD 23.40
- PolyPhen-2 0.66
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available