S16G (p.Ser16Gly) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
S16G (p.Ser16Gly) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S16G (p.Ser16Gly) variant details
- p.Ser16Gly
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.09
- MetaLR 0.01
- MetaSVM -0.86
- CADD 17.80
- PolyPhen-2 0.01
- SIFT 0.33
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available