S105L (p.Ser105Leu) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
S105L (p.Ser105Leu) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
S105L (p.Ser105Leu) variant details
- p.Ser105Leu
- gnomAD X-105195706-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.558
- REVEL 0.54
- MetaLR 0.41
- MetaSVM -0.20
- CADD 23.60
- PolyPhen-2 0.34
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available