M21T (p.Met21Thr) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
M21T (p.Met21Thr) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
M21T (p.Met21Thr) variant details
- p.Met21Thr
- NCI-TCGA TCGA novel
- gnomAD rs1930334023
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.18
- MetaLR 0.01
- MetaSVM -0.79
- CADD 18.50
- PolyPhen-2 0.01
- SIFT 0.24
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available