M125V (p.Met125Val) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
M125V (p.Met125Val) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
M125V (p.Met125Val) variant details
- p.Met125Val
- gnomAD rs1556198556
- Missense
- Variant Prioritization Score for Impact Estimate 0.549
- REVEL 0.58
- MetaLR 0.51
- MetaSVM -0.19
- CADD 23.30
- PolyPhen-2 0.93
- SIFT 0.03
- Population evidence available
- Structural context available