L9I (p.Leu9Ile) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
L9I (p.Leu9Ile) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
L9I (p.Leu9Ile) variant details
- p.Leu9Ile
- gnomAD X-104658938-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.12
- MetaLR 0.01
- MetaSVM -0.69
- CADD 19.60
- PolyPhen-2 0.90
- SIFT 0.76
- Population evidence available
- Structural context available
- Literature evidence available