L7S (p.Leu7Ser) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
L7S (p.Leu7Ser) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
L7S (p.Leu7Ser) variant details
- p.Leu7Ser
- gnomAD X-104658933-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.26
- MetaLR 0.02
- MetaSVM -0.79
- CADD 23.70
- PolyPhen-2 0.97
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available