L19P (p.Leu19Pro) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
L19P (p.Leu19Pro) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
L19P (p.Leu19Pro) variant details
- p.Leu19Pro
- gnomAD X-104658969-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.27
- MetaLR 0.02
- MetaSVM -0.98
- CADD 23.50
- PolyPhen-2 0.38
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available