I88V (p.Ile88Val) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
I88V (p.Ile88Val) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
I88V (p.Ile88Val) variant details
- p.Ile88Val
- gnomAD X-105195654-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.12
- MetaLR 0.02
- MetaSVM -0.87
- CADD 19.00
- PolyPhen-2 0.41
- SIFT 0.37
- Population evidence available
- Structural context available
- Literature evidence available