C12Y (p.Cys12Tyr) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
C12Y (p.Cys12Tyr) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
C12Y (p.Cys12Tyr) variant details
- p.Cys12Tyr
- TOPMed rs1930333113
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.06
- MetaLR 0.01
- MetaSVM -0.87
- CADD 12.70
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available