A45S (p.Ala45Ser) variant of IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2)
A45S (p.Ala45Ser) in IL1RAPL2 (X-linked interleukin-1 receptor accessory protein-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
A45S (p.Ala45Ser) variant details
- p.Ala45Ser
- gnomAD X-105195525-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.31
- MetaLR 0.35
- MetaSVM -0.45
- CADD 21.60
- PolyPhen-2 0.46
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available