V12S (p.Val12Ser) variant of IL17F (Interleukin-17F)
V12S (p.Val12Ser) in IL17F (Interleukin-17F) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
V12S (p.Val12Ser) variant details
- p.Val12Ser
- gnomAD 6-52238949-AC-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.451
- CADD 33.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available