V12D (p.Val12Asp) variant of IL17F (Interleukin-17F)
V12D (p.Val12Asp) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
V12D (p.Val12Asp) variant details
- p.Val12Asp
- gnomAD rs1480169308
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.37
- MetaLR 0.12
- MetaSVM -1.05
- CADD 23.70
- PolyPhen-2 0.85
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available