S54R (p.Ser54Arg) variant of IL17F (Interleukin-17F)
S54R (p.Ser54Arg) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S54R (p.Ser54Arg) variant details
- p.Ser54Arg
- TOPMed rs1372951889
- gnomAD rs1372951889
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.14
- MetaLR 0.05
- MetaSVM -1.06
- CADD 21.90
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available