S46G (p.Ser46Gly) variant of IL17F (Interleukin-17F)
S46G (p.Ser46Gly) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
S46G (p.Ser46Gly) variant details
- p.Ser46Gly
- gnomAD rs1303812954
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.08
- MetaLR 0.02
- MetaSVM -1.07
- CADD 7.22
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available