S18W (p.Ser18Trp) variant of IL17F (Interleukin-17F)
S18W (p.Ser18Trp) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
S18W (p.Ser18Trp) variant details
- p.Ser18Trp
- gnomAD 6-52238931-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.14
- MetaLR 0.03
- MetaSVM -1.08
- CADD 13.10
- PolyPhen-2 0.34
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available