S18* (p.Ser18Ter) variant of IL17F (Interleukin-17F)
S18* (p.Ser18Ter) in IL17F (Interleukin-17F) is a protein-truncating change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
S18* (p.Ser18Ter) variant details
- p.Ser18Ter
- rs145598353
- ClinGen CA364445287
- ClinVar RCV001988577
- 1000Genomes rs145598353
- Likely benign
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.282
- AlphaMissense 0.07
- MetaLR 0.01
- MetaSVM -0.93
- PolyPhen-2 0.00
- SIFT 1.00
- EVE 0.03
- EBI: Likely benign
- UniProt: Likely benign
- Population evidence available
- Structural context available