M70K (p.Met70Lys) variant of IL17F (Interleukin-17F)
M70K (p.Met70Lys) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
M70K (p.Met70Lys) variant details
- p.Met70Lys
- ExAC rs754344583
- gnomAD rs754344583
- Missense
- Variant Prioritization Score for Impact Estimate 0.095
- REVEL 0.06
- MetaLR 0.02
- MetaSVM -1.07
- CADD 5.29
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available