L17R (p.Leu17Arg) variant of IL17F (Interleukin-17F)
L17R (p.Leu17Arg) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L17R (p.Leu17Arg) variant details
- p.Leu17Arg
- ExAC rs746999872
- gnomAD rs746999872
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.36
- MetaLR 0.16
- MetaSVM -0.79
- CADD 23.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available