L17M (p.Leu17Met) variant of IL17F (Interleukin-17F)
L17M (p.Leu17Met) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
L17M (p.Leu17Met) variant details
- p.Leu17Met
- gnomAD 6-52238935-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.25
- MetaLR 0.11
- MetaSVM -1.03
- CADD 16.70
- PolyPhen-2 0.98
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available