K4E (p.Lys4Glu) variant of IL17F (Interleukin-17F)
K4E (p.Lys4Glu) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
K4E (p.Lys4Glu) variant details
- p.Lys4Glu
- gnomAD 6-52244420-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0688
- REVEL 0.01
- MetaLR 0.02
- MetaSVM -1.06
- CADD 3.34
- PolyPhen-2 0.24
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available