K43E (p.Lys43Glu) variant of IL17F (Interleukin-17F)
K43E (p.Lys43Glu) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
K43E (p.Lys43Glu) variant details
- p.Lys43Glu
- gnomAD rs1211948877
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.07
- MetaLR 0.03
- MetaSVM -1.12
- CADD 7.43
- PolyPhen-2 0.12
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available