I62S (p.Ile62Ser) variant of IL17F (Interleukin-17F)
I62S (p.Ile62Ser) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
I62S (p.Ile62Ser) variant details
- p.Ile62Ser
- gnomAD 6-52238799-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.09
- MetaLR 0.04
- MetaSVM -1.02
- CADD 17.70
- PolyPhen-2 0.01
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available