I62L (p.Ile62Leu) variant of IL17F (Interleukin-17F)
I62L (p.Ile62Leu) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
I62L (p.Ile62Leu) variant details
- p.Ile62Leu
- gnomAD 6-52238800-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.04
- MetaLR 0.01
- MetaSVM -1.00
- CADD 6.97
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available