I59T (p.Ile59Thr) variant of IL17F (Interleukin-17F)
I59T (p.Ile59Thr) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
I59T (p.Ile59Thr) variant details
- p.Ile59Thr
- ExAC rs769515909
- TOPMed rs769515909
- gnomAD rs769515909
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.11
- MetaLR 0.05
- MetaSVM -1.04
- CADD 14.00
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available