G8V (p.Gly8Val) variant of IL17F (Interleukin-17F)
G8V (p.Gly8Val) in IL17F (Interleukin-17F) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
G8V (p.Gly8Val) variant details
- p.Gly8Val
- rs533677189
- NCI-TCGA Cosmic COSV6023
- 1000Genomes rs533677189
- ExAC rs533677189
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0655
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -1.07
- CADD 0.04
- PolyPhen-2 0.00
- SIFT 0.27
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the 1KG:GIH population (allele frequency 0.005)
- Structural context available