G37R (p.Gly37Arg) variant of IL17F (Interleukin-17F)
G37R (p.Gly37Arg) in IL17F (Interleukin-17F) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G37R (p.Gly37Arg) variant details
- p.Gly37Arg
- rs765796484
- NCI-TCGA Cosmic COSV1002
- ExAC rs765796484
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.17
- MetaLR 0.08
- MetaSVM -1.06
- CADD 10.10
- PolyPhen-2 0.74
- SIFT 0.06
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available