F41C (p.Phe41Cys) variant of IL17F (Interleukin-17F)
F41C (p.Phe41Cys) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
F41C (p.Phe41Cys) variant details
- p.Phe41Cys
- gnomAD 6-52238862-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.10
- MetaLR 0.06
- MetaSVM -1.06
- CADD 14.70
- PolyPhen-2 0.64
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available