D58A (p.Asp58Ala) variant of IL17F (Interleukin-17F)
D58A (p.Asp58Ala) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
D58A (p.Asp58Ala) variant details
- p.Asp58Ala
- gnomAD 6-52238811-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.26
- MetaLR 0.11
- MetaSVM -0.92
- CADD 23.50
- PolyPhen-2 0.67
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available