A28S (p.Ala28Ser) variant of IL17F (Interleukin-17F)
A28S (p.Ala28Ser) in IL17F (Interleukin-17F) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A28S (p.Ala28Ser) variant details
- p.Ala28Ser
- ExAC rs777234343
- gnomAD rs777234343
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.09
- MetaLR 0.03
- MetaSVM -1.06
- CADD 5.52
- PolyPhen-2 0.01
- SIFT 0.67
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available