A23V (p.Ala23Val) variant of IL17F (Interleukin-17F)
A23V (p.Ala23Val) in IL17F (Interleukin-17F) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Candidiasis, familial, 6. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes structural context.
A23V (p.Ala23Val) variant details
- p.Ala23Val
- rs2128267834
- ClinGen CA364445256
- ClinVar RCV003002672
- Uncertain significance
- Candidiasis, familial, 6
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- AlphaMissense 0.41
- MetaLR 0.09
- MetaSVM -0.98
- PolyPhen-2 0.99
- SIFT 0.01
- EVE 0.23
- ClinVar: Uncertain significance (Candidiasis, familial, 6)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available