T111M (p.Thr111Met) variant of IL15RA (Q13261)
T111M (p.Thr111Met) in IL15RA (Q13261) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as benign in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
T111M (p.Thr111Met) variant details
- p.Thr111Met
- rs41294171
- ClinGen CA5397137
- cosmic curated COSV66093
- ClinVar RCV000950183
- Benign
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.03
- CADD 21.40
- PolyPhen-2 0.03
- SIFT 0.10
- ClinVar: Benign (not provided)
- EBI: Benign
- UniProt: Benign
- Most common in the HGDP:DAI population (allele frequency 0.11)
- Structural context available