R56W (p.Arg56Trp) variant of IL15RA (Q13261)
R56W (p.Arg56Trp) in IL15RA (Q13261) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
R56W (p.Arg56Trp) variant details
- p.Arg56Trp
- rs773161996
- ExAC rs773161996
- TOPMed rs773161996
- gnomAD rs773161996
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.549
- REVEL 0.61
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available