L22Q (p.Leu22Gln) variant of IL15RA (Q13261)
L22Q (p.Leu22Gln) in IL15RA (Q13261) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L22Q (p.Leu22Gln) variant details
- p.Leu22Gln
- Ensembl rs1838639341
- Uncertain significance
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.20
- CADD 24.30
- PolyPhen-2 0.99
- SIFT 0.01
- ClinVar: Uncertain significance (not specified)
- UniProt: Uncertain significance
- Population evidence available
- Structural context available