Y66F (p.Tyr66Phe) variant of IFNGR1 (Interferon gamma receptor 1)
Y66F (p.Tyr66Phe) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
Y66F (p.Tyr66Phe) variant details
- p.Tyr66Phe
- Ensembl rs867775070
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- REVEL 0.55
- CADD 24.90
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available