V68I (p.Val68Ile) variant of IFNGR1 (Interferon gamma receptor 1)
V68I (p.Val68Ile) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V68I (p.Val68Ile) variant details
- p.Val68Ile
- TOPMed rs1159939937
- gnomAD rs1159939937
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.09
- CADD 11.70
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available