T21P (p.Thr21Pro) variant of IFNGR1 (Interferon gamma receptor 1)
T21P (p.Thr21Pro) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T21P (p.Thr21Pro) variant details
- p.Thr21Pro
- Ensembl rs1779788367
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.23
- CADD 5.07
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available