S97C (p.Ser97Cys) variant of IFNGR1 (Interferon gamma receptor 1)
S97C (p.Ser97Cys) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
S97C (p.Ser97Cys) variant details
- p.Ser97Cys
- gnomAD rs1327760525
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.42
- CADD 22.60
- PolyPhen-2 0.98
- SIFT 0.05
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available