S27F (p.Ser27Phe) variant of IFNGR1 (Interferon gamma receptor 1)
S27F (p.Ser27Phe) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
S27F (p.Ser27Phe) variant details
- p.Ser27Phe
- ExAC rs770509341
- gnomAD rs770509341
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.27
- CADD 23.40
- PolyPhen-2 0.92
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available