R16W (p.Arg16Trp) variant of IFNGR1 (Interferon gamma receptor 1)
R16W (p.Arg16Trp) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R16W (p.Arg16Trp) variant details
- p.Arg16Trp
- ExAC rs758608616
- gnomAD rs758608616
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.35
- AlphaMissense 0.47
- MetaLR 0.09
- MetaSVM -0.98
- CADD 0.24
- PolyPhen-2 0.01
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available