R105S (p.Arg105Ser) variant of IFNGR1 (Interferon gamma receptor 1)
R105S (p.Arg105Ser) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R105S (p.Arg105Ser) variant details
- p.Arg105Ser
- TOPMed rs1402033609
- gnomAD rs1402033609
- cosmic curated COSV62990
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.28
- CADD 12.70
- PolyPhen-2 0.22
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available