P57A (p.Pro57Ala) variant of IFNGR1 (Interferon gamma receptor 1)
P57A (p.Pro57Ala) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P57A (p.Pro57Ala) variant details
- p.Pro57Ala
- TOPMed rs1348102762
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.28
- CADD 11.40
- PolyPhen-2 0.72
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available